Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- - Names and Identifiers
Name | Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-
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Synonyms | (S)-α,α-BIS(3,5-BIS(TRIFLUOROMET (S)-α,α-[3,5-Bis(trifluoroMethyl)phenyl]prolinol triMethylsilyl ether (S)-2-[(Bis(3,5-bis(trifluoroMethyl)phenyl)triMethylsilanyloxy)Methyl]pyrrolidine Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- (S)-2-[(Bis(3,5-Bis(Trifluoromethyl)Phenyl)Trimethylsilanyloxy)Methyl]Pyrrolidine, (S)-2-[(Bis(3,5-Bis(Trifluoromethyl)Phenyl)Trimethylsilyloxy)Methyl]Pyrrolidine, (S)-Α,Α-[3,5-Bis(Trifluoromethyl)Phenyl]Prolinol Trimethylsilyl Ether (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether
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CAS | 848821-61-4
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Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- - Physico-chemical Properties
Molecular Formula | C24H23F12NOSi
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Molar Mass | 597.51 |
Density | 1.319±0.06 g/cm3(Predicted) |
Melting Point | 48-56°C |
Boling Point | 382.4±37.0 °C(Predicted) |
Flash Point | 110°C |
pKa | 9.34±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
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WGK Germany | 3 |
Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- - Introduction
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-, also known as (2S)-Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C24H26F6NOSi
-Molecular weight: 500.55g/mol
-Melting point: No data
-Boiling Point: No data
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane
Use:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-is often used as a chiral catalyst in chemical synthesis
-It is widely used in organic synthesis reactions, such as asymmetric hydrogenation, asymmetric methylation, asymmetric olefin cyclization, etc.
Preparation Method:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-can be prepared by reacting compounds containing corresponding functional groups
-Usually the silicon ether compound is reacted with a chiral amine to form a chiral silicon ether
Safety Information:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-has limited safety information, so general laboratory safety operation specifications should be followed when using
-It should be operated under good ventilation and avoid contact with skin and eyes
-Wear appropriate protective equipment such as gloves and goggles when using it
-In case of accidental inhalation or ingestion, seek medical attention immediately and provide the technical safety data sheet to the doctor for reference
Please note that this is only an introduction of some basic information about Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-specific uses and preparation methods may require more detailed research and practice. When using this substance, always consult the relevant literature and reliable sources and strictly observe the relevant safety procedures.
Last Update:2024-04-10 22:29:15